For optimal results, it is generally recommended to take Everest Manjishtadi Kashyam twice daily. Typically, a dosage of 10-15 ml mixed with an equal amount of water is advised. It's best to consume this on an empty stomach, ideally before meals. However, individual needs may vary, so it's wise to consult with a healthcare professional or an Ayurvedic practitioner for personalized advice tailored to your health requirements.