It's generally safe to use Sitaram Poothikasavam alongside other herbal supplements, but it's crucial to consider potential interactions between ingredients. Since Sitaram Poothikasavam is an Ayurvedic tonic, it may have herbal components that interact with others. For personalized advice, consult with a healthcare professional or an Ayurvedic practitioner who can evaluate your specific health needs and existing supplement regimen. Always ensure that any combination of supplements aligns with your health goals and does not lead to unintended side effects.