High AST and ALT Levels After Autoimmune RA Treatment - #47993

High AST & ALT can occur due to Sulfasalazine (common side effect)

What to do Do NOT stop medicine suddenly Inform your rheumatologist immediately Doctor may reduce dose / stop drug / change medicine Avoid alcohol, fatty food, unnecessary supplements Repeat LFT after 1–2 weeks

Supportive care Light diet, good hydration Avoid other liver-toxic drugs

ELEVATED AST AND ALT AFTER STARTING SALFAZALAZINE IS A KNOWN AND IMPORTANT ISSUE AND IT NEEDS CALM BUT TIMELY ACTION PLEASE DO NOT PANIC BUT ALSO DO NOT IGNORE THIS

SALFAZALAZINE CAN CAUSE LIVER ENZYME ELEVATION IN SOME PEOPLE ESPECIALLY WITHIN THE FIRST FEW MONTHS THIS DOES NOT ALWAYS MEAN PERMANENT DAMAGE BUT IT DOES MEAN THE LIVER IS UNDER STRESS THE ASSOCIATED FATIGUE YOU ARE FEELING SUPPORTS THIS

THE FIRST AND MOST IMPORTANT STEP IS DO NOT STOP SALFAZALAZINE ON YOUR OWN PLEASE INFORM YOUR RHEUMATOLOGIST OR PRESCRIBING DOCTOR IMMEDIATELY THEY MAY REDUCE THE DOSE TEMPORARILY HOLD THE MEDICINE OR SWITCH TO AN ALTERNATIVE DMARD DEPENDING ON HOW HIGH THE VALUES ARE

THIS DECISION MUST BE MEDICAL BECAUSE RA ALSO NEEDS CONTROL

IN THE MEANTIME THERE ARE VERY IMPORTANT THINGS YOU SHOULD DO

ABSOLUTELY AVOID ALCOHOL PAINKILLERS LIKE PARACETAMOL UNLESS ADVISED HERBAL MIXTURES OR STRONG AYURVEDIC FORMULATIONS WITHOUT GUIDANCE FRIED PACKAGED AND VERY SPICY FOODS

FOCUS ON LIVER FRIENDLY DIET SIMPLE HOME COOKED FOOD MORE VEGETABLES LESS OIL STEAMED OR BOILED FOODS ADEQUATE PROTEIN BUT NOT EXCESS PLENTY OF WATER

TAKE

AROGYAVARDINI VATI ONE TABLET TWICE DAILY AFTER FOOD WITH WSRM WATER

BHUMYAMALAKI POWDER HALF TEASPOON ONCE DAILY WITH WARM WATER GILOY JUICE 5 ML TWICE DAILY AFTER FOOD

FATIGUE IS A SIGNAL FROM THE BODY TO SLOW DOWN ENSURE ADEQUATE REST SLEEP AND DO NOT PUSH YOURSELF PHYSICALLY

REPEAT LIVER FUNCTION TESTS ARE USUALLY DONE AFTER DOSE ADJUSTMENT OR TEMPORARY PAUSE AND IN MANY CASES VALUES COME DOWN ONCE THE MEDICINE IS MODIFIED

IF YOU NOTICE YELLOWING OF EYES OR SKIN DARK URINE SEVERE NAUSEA OR VOMITING RIGHT UPPER ABDOMINAL PAIN PLEASE SEEK MEDICAL ATTENTION IMMEDIATELY

THIS IS A RECOGNIZED SIDE EFFECT IT IS OFTEN REVERSIBLE DO NOT SELF STOP RA MEDICINE COORDINATE WITH YOUR DOCTOR SUPPORT THE LIVER GENTLY AND AVOID ANY ADDITIONAL LOAD