The Variola major virus, which caused smallpox, was one of the deadliest diseases in human history, but thanks to the global vaccination campaign, it was officially eradicated in 1980. While official stocks of the virus are stored in high-security labs in the U.S. and Russia for research purposes, the risk of accidental release is considered extremely low due to strict safety measures. However, concerns about bioterrorism or synthetic recreation of the virus remain, as advancements in genetic engineering could, in theory, allow for its reconstruction. If smallpox were ever reintroduced, modern medicine—including stockpiled smallpox vaccines—would likely be our first line of defense, but the effectiveness of these vaccines against a genetically modified strain remains uncertain.
In Ayurveda, historical texts like the Charaka Samhita and Sushruta Samhita mention treatments for Masurika, which many scholars believe referred to smallpox or similar eruptive diseases. Traditional approaches focused on immune-strengthening herbs like Giloy (Tinospora cordifolia), Ashwagandha, and Tulsi, along with detoxifying therapies like Panchakarma to purify the body. Certain topical applications, such as neem paste or turmeric, were used to soothe skin lesions, and a cooling diet was often recommended to balance excess heat in the body. While these treatments likely helped manage symptoms and boost immunity, they would not replace vaccination or antiviral therapies in the case of a modern outbreak.
If a disease like Variola major were to resurface today, Ayurvedic principles could still support immunity and overall resilience, but they would not serve as a stand-alone cure. Ayurveda’s focus on building ojas (vital energy) through proper diet, lifestyle, and herbal remedies could complement conventional treatments. Preventative measures such as nasya (nasal oil application), pranayama (breathing exercises), and daily consumption of Rasayana herbs might enhance immune defenses. While fascinating from a historical perspective, fighting a virus as deadly as smallpox would still require modern medical interventions, including vaccines and antiviral treatments, alongside natural immunity-boosting practices.
The thought of Variola major coming back is indeed unsettling! You’re right, the virus exists in some labs, but its resurgence is pretty unlikely. The concern over accidental release though, it’s reasonable to have some unease about that. In the meantime, let’s delve into Ayurveda’s perspective on immunity building.
Ayurveda doesn’t have direct records of treating smallpox, obviously, it’s a more modern epidemic. But, it does have profound wisdom on boosting immunity. Known as “Ojas”, immunity in Ayurveda is all about balance. A good diet is key. Including herbs like Guduchi (Tinospora cordifolia), Ashwagandha (Withania somnifera), and Tulsi (Ocimum sanctum) helps boost overall resilience. These are packed with natural compounds to support your immune system. You’d take Guduchi decoctions regularly, safe for most—2-3g twice day in warm water after meals.
Then there’s Rasayana therapy, rejuvenators that nourish the tissues, or dhatus. Chyawanprash, made of Amla and other herbs, enhances this foundational vitality. You can find it pretty much in health stores, a spoonful in warm milk each morning could work wonders.
Balancing the doshas is pivotal, too, like keeping the vata in check during cold weather. Warm foods, oils, yoga practices adapted to one’s prakriti (constitution) keeps you stable. Don’t forget Agni, or digestive fire, either; ensure it’s strong by avoiding heavy, cold, oily foods.
While none of these might directly “treat” smallpox if it came back, they’re about keeping the body in a state that can fend off issues before they even begin. Still, if there would be a new outbreak, modern medicine, especially vaccines, would be your best defense. The Ayurvedic lifestyle supports overall health, but doesn’t replace urgent interventions when needed.


