Managing High TSH and HBA1C Levels - #47102
I am Neeraj Gupta, 57 yrs old man, My HBA1C : 6.9, Urine Glucose and Acetone is NIL. TSH : 7 (T3: 1.14 & T4: 9.2 to 10.2 , Normal ) Total Cholestrol is 215. TGL : 160, LDL : 125, HDL : 50. I am 5'9" High, Weight : 64 KG. Weight remain Consistence with +/- 1 kg. Vegiterian, Disiplined Routine for meal times. No Junk Food, simple Daal, Chawal, Vegitable and Roti / multigrain Roti. I do not feel fatigue, blur vision, etc. LFT / KFT is normal. It is said that High TSH can also elevate HBA1C and Cholestrol. Pl. guide me If I have take medicine for all or I should take care one by one.If one by one which one ?
How long have you been aware of your elevated TSH levels?:
- More than 6 monthsHave you made any lifestyle changes recently that could affect your thyroid or blood sugar levels?:
- No changesDo you have any family history of thyroid disorders or diabetes?:
- No family history

Doctors' responses
Mr. Neeraj Gupta ji, thank you for sharing very clear and complete details. Your question is thoughtful and clinically very relevant. I’ll answer point-by-point and then give a priority-wise plan. 1. Understanding your reports (in simple terms) 🔹 Blood Sugar HbA1c: 6.9% This falls in early diabetes / borderline diabetes range. Urine sugar & acetone NIL → good sign (no uncontrolled diabetes). No symptoms → early stage, reversible with correct strategy.
🔹 Thyroid TSH: 7 mIU/L T3 & T4: Normal ➡️ This is called Subclinical Hypothyroidism. ✔ Very important point you mentioned is 100% correct: High TSH can raise HbA1c and cholesterol This is well proven medically.
🔹 Lipids Total Cholesterol: 215 (borderline high) LDL: 125 (mildly high) Triglycerides: 160 (mildly high) HDL: 50 (good)
➡️ Pattern strongly suggests thyroid-related dyslipidemia, not lifestyle-related (because your diet & weight are excellent).
2. Do you need medicine for all three together? ❌ No — NOT all together ✅ YES — one by one, in the correct order
🔑 Correct Priority Order 1️⃣ Thyroid → 2️⃣ Sugar → 3️⃣ Cholesterol
Because thyroid dysfunction is the root trigger here.
3. Why THYROID should be treated first Subclinical hypothyroidism can: Increase insulin resistance → raises HbA1c Reduce LDL clearance → raises cholesterol Slow metabolism even without symptoms
📌 In many patients: Treating thyroid alone lowers HbA1c by 0.3–0.6 Improves cholesterol without statins
4. My Practical Recommendation (Step-wise) ✅ Step 1: Start LOW-DOSE Thyroid Treatment Because: Age > 55 TSH persistently > 6 for > 6 months Associated metabolic changes (HbA1c + lipids)
🟢 Levothyroxine 25 mcg once daily Empty stomach Morning Wait 30–45 min before tea/food ⏳ Recheck after 6–8 weeks TSH HbA1c Lipid profile 👉 Many times, no further medicines are needed after this step
✅ Step 2: Watch HbA1c (No immediate diabetes medicine) At present: HbA1c 6.9 No symptoms Normal weight Disciplined diet ✔ I would NOT start diabetes medication now Instead:
Continue current diet Reduce rice quantity slightly Add post-meal walk (15–20 min) Reassess after thyroid correction.
✅ Step 3: Cholesterol — Only if still high Given your lifestyle: If after thyroid normalization LDL remains >130 → then only consider medicine Otherwise no statin needed now
5. Important Dietary Fine-Tuning (Minor, not major) You’re already doing very well. Just refine: Reduce white rice portion Prefer: Millet / barley / oats (rotational) Add: 1 tsp soaked flaxseed daily Handful of nuts (walnut/almond)
Avoid: Excess evening carbs
Tq

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